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Its exact mechanism of action is not known, but it may be due to general central nervous system depression. Its exact mechanism of action is not known, but it may be due to general central nervous system depression. The recommended dose for adults and children over 12 years of age is one 800 mg tablet three to four times a day Skelaxin (active ingredient – metaxalone) is a muscle relaxant that is used to relieve pain caused by sprains, strains, and other musculoskeletal conditions and to relax muscles. The recommended dose for adults and children over 12 years of age is one 800 mg tablet three to four times a day Skelaxin (active is aggrenox considered a blood thinner ingredient – metaxalone) is a muscle relaxant that is used to relieve pain caused by sprains, strains, and other musculoskeletal conditions and to relax muscles. Physician Prescribing Information ; SKELAXIN U. Physician Prescribing Information ; SKELAXIN U. Told me to take as needed (didn’t have to take the full bottle). 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If the pain is from nerves, medications like Lyrica or gabapentin sometimes help. I have a question about the skelaxin. I have a question about the skelaxin. You may need a dose adjustment or special tests to safely take Skelaxin. You may need a dose adjustment or special tests to safely take Skelaxin. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Physician Prescribing Information ; SKELAXIN U. Physician Prescribing Information ; SKELAXIN U. Drug class: Skeletal muscle relaxants. Drug class: Skeletal muscle relaxants. Please let us know how he is doing. Please let us know how he is doing. Gastrointestinal upset, including nausea and vomiting. Gastrointestinal upset, including nausea and vomiting. 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